Revealed of Rare Primary Lyphoepithelionma-Like Carcinoma of the Lung
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Lymphoepithelioma-like carcinoma (LELC) is a rare type of cancer that usually occurs in the pharynx and foregut-derivative organs, including the salivary glands, thymus, stomach and liver . Primary lung LELC is a rare subtype of non-small cell lung cancer, accounting for about 0.92% of other lung cancer types. Lymphoepitheliomatoid carcinoma of the lung was first reported by Begin LR et al. in 1987.Lung LELC is a large, centrally placeholder tumor with a smooth edge in imaging[4]. The diagnosis of lung LELC is mainly dependent on pathological and immunohistochemical results. Histologically, it is difficult to differentiate lung LELC from metastatic nasopharyngeal carcinoma. The diagnosis must be combined with the patient's history, endoscopy or magnetic resonance imaging (MRI) to evaluate whether the tumor is metastasized from nasopharyngeal tumor. Primary lung LELC can be diagnosed after exclusion of nasopharyngeal malignancy as a source. 18F-FDG PET/CT examination has important application value in the diagnosis of pulmonary nodules or masses. Therefore, this study conducted a brief review of relevant literature.